Department of Biotechnology
Dr. Santosh Kumar H SM.Sc (Biochemistry), Advanced Diploma in Bioinformatics, Ph. D (Biochemistry),
- 9164807211
- sk.genesan@gmail.com, skhs@kuvempu.ac.in
Area Of Research
Biochemistry and Bioinformatics
About the Faculty
Short note from the faculty
Awards
| Sl No | Award Name | Award For | Organization | Year |
|---|---|---|---|---|
| 1 | Best Research Presentation award | Oral Presentation of research work | Society of Biological Chemists (India) | 2014 |
| 2 | Young Scientist Award | Best poster presentation | SUNY,Buffallo and Vellore Institute of Technology | 2012 |
| 3 | Best Poster Award | Poster Presentation | SDM college, Ujire | 2008 |
Journals Publications
| Sl No | Authors | Title | Impact Factor | Publisher | Year |
|---|---|---|---|---|---|
| 1 | antosh H. S. Kumar & Sudeep D. Ghate Tamizh G. Selvan, Pavan Gollapalli | Early diagnostic and prognostic biomarkers for gastric cancer: systems-level molecular basis of subsequent alterations in gastric mucosa from chronic atrophic gastritis to gastric cancer | 3.6 | j. genet. engg. Biotech. | 2023-08-18 |
| 2 | Pavan Gollapalli · Sushmitha Rudrappa · Vadlapudi Kumar · Hulikal Shivashankara Santosh Kumar | Domain Architecture Based Methods for Comparative Functional Genomics Toward Therapeutic Drug Target Discovery | 3.9 | Journal of Molecular Evolution/ Springer Nature | 2023-08-06 |
| 3 | H. S. Rudresh, T. Divyashree, N.S Yathisha, V. Dwarakanath, H.S. Santosh Kumar and R. G. Sharathchan | Comparative Analysis of Desiccation Tolerance in Oeosporangium elegans and Mickelopteris cordata | 1.34 | Springer/ Vegetos | 2023-07-10 |
| 4 | Ashok AK, Gnanasekaran TS, Santosh Kumar HS, Srikanth K, Prakash N, Gollapalli P. | High-throughput screening and molecular dynamics simulations of natural products targeting LuxS/AI-2 system as a novel antibacterial strategy for antibiotic resistance in Helicobacter pylori. | 5.2 | Journal of Biomolecular Structure and Dynamics. 2023 May 5:1-6. | 2023-05-09 |
| 5 | Gollapalli P, Selvan GT, Santosh kumar HS, Ballamoole KK. | Functional insights of antibiotic resistance mechanism in Helicobacter pylori: Driven by gene interaction network and centrality-based nodes essentiality analysis. | 3.98 | Microbial Pathogenesis | 2022-10-01 |
| 6 | Shimoga V Sunil, Hulikal S Santosh Kumar, Siddanakoppalu N Pramod, Betadthunga T Prabhakar, Mahanthe | Characterization and biochemical activities of novel functional antimicrobial peptide (AMP) from Trichogramma chilonis | 0.109 | Biomedicine | 2022-05-10 |
| 7 | Sunil SV, Kerima OZ, Santosh Kumar HS, Prabhakar BT, Pramod SN, Niranjana P. | In Silico Characterization of a Transcript Code Based Screening of Antimicrobial Peptide from Trichogramma chilonis. | 2.69 | International Journal of Peptide Research and Therapeutics. | 2021-12-27 |
| 8 | Poornima Ramesh; Jayashree Honnebailu Nagendrappa; Santosh Kumar HS | Comparative analysis of rosetta Stone events in Klebsiella pneumoniae and Streptococcus pneumoniae for drug target identification. | 1 | Beni-Suef University Journal of Basic and Applied Sciences/Springer Open - In press | 2021-05-01 |
| 9 | H. L. Raghavendra, B. R. Bharath, T. R. Prashith Kekuda, D. M. Chetan, M. M. V. N. L. Chaitanya and | Understanding Pharmacodynamics of Butyl Isobutyl Phthalate: Where In vitro and In silico Studies Converge | 0.721 | Indian Journal Pharmaceutical Sciences/ The Indian Pharmaceutical Association | 2021-03-10 |
| 10 | Triveni N, Santosh kumar H. S. Vootla Shyamkumar | Nuclear polyhedrosis virus induced proteomic changes in Antheraea mylitta | 1.78 | Physiological Entomology/ Wiley International Publication, Royal Society of Entomology | 2021-01-04 |
| 11 | H. S. Santosh Kumar, S. Ravi Kumar, N. Naveen Kumar, S. Ajith | Molecular docking studies of gyrase inhibitors: weighing earlier screening bedrock | 1 | Insilico Pharmacology/ Springer Nature | 2021-01-01 |
| 12 | Jaginakere Vasanthkumar Akshatha,Hulikal Shivashankara Santhosh kumar,Harishchandra Sripathy Prakash | In silico docking studies of α-amylase inhibitors from the anti-diabetic plant Leucas ciliata Benth., and endophytic, Streptomyces longisporoflavus from Western Ghats, southern India | 1.78 | 3Biotech / Springer Verlag | 2020-11-06 |
| 13 | Rajeshwara Achur Praveen Kumar, Chinnappa Appattira Uthaiah, Santhosha Sangapurada Mahantheshappa, N | Antiproliferative potential, quantitative structure-activity relationship, cheminformatic and molecular docking analysis of quinoline and benzofuran derivatives | 0.78 | European Journal of Chemistry/ Atlanta Publishing House | 2020-08-27 |
| 14 | Sharat kumar Pattar, Riaz Mahmood, Sushil Kumar Jalali, Santosh kumar HS | Activity of Metabolic enzymes towards exhibiting insecticide resistance in lepidopteran insect pest: An in-vitro and in-silico studies | 0.7 | Plant Archives | 2020-07-11 |
| 15 | Praveen Kumar Dhenya Naik , Nayak Devappa Satyanarayan , Subba Rao Venkata Madhunapantula , Hulikal | In silico screening for the interaction of small molecules with their targets and evaluation of therapeutic efficacy by free online tools | 0.78 | Atlanta Publishing House/ European Journal of Chemistry | 2020-04-05 |
| 16 | Nallabothula Triveni, Avabrath Nagashree Krishna Hulikal Shivashankara Santosh Kumar, Shyam Kumar v | PI3K-Akt pathway mediated antiviral mechanism in silkworm Antheraea mylitta | 0.75 | Springer Nature/ Virus Disease | 2020-04-04 |
| 17 | Sannanegunda Venkatarama Bhatta Krishnamurthy Shreyas Raghunath, Chethankumar Masaruru Veerabhadrapp | Nuclear Abnormalities in Erythrocytes of Frogs from Wetlands and Croplands of Western Ghats Indicate Environmental Contaminations | 0.7 | THE JOURNAL OF TROPICAL LIFE SCIENCE | 2017-01-09 |
| 18 | Rizwana Abid, Hulikal Shivashankara Santosh Kumar, Riaz Mahmood | Hypolipidemic and antioxidant effects of ethanol extract of Cassia fistula fruit in hyperlipidemic mice | 1.241 | Pharmaceutical Biology/Taylor and Franscis | 2016 |
| 19 | Hulikal Shivashankara Santosh kumar, , Sandeep Telkar, Vadlapudi Kumar, Sharath Pattar | Towards the construction of an interactome for Human WD40 protein family | 0.6 | Bioinfromation/Biomedical Informatics | 2016 |
| 20 | Hulikal Shivashankara Santosh Kumar, Vadlapudi Kumar | A Comparison of Rosetta Stones in Adapter Protein Families | 0.6 | Bioinformation/Biomedical Informatics | 2016 |
| 21 | J.Ramprasad, Nagabhushana Nayak, Udayakumar D, P. Yogeeswari, D. Sriram, S K Peethambar, Rajeshwara | Synthesis and biological evaluation of new imidazo[2,1-b][1,3,4]thiadiazole-benzimidazole derivatives. | 4.519 | European Journal of medicinal Chemistry/Elsevier | 2015 |
| 22 | Nagabhushana Nayak, Jurupula Ramprasad, Udayakumar Dalimba, Perumal Yogeeswari, Dharmarajan Sriram, | Synthesis of new pyrazole-triazole hybrids by click reaction using a green solvent and evaluation of their antitubercular and antibacterial activity | 1.369 | Research on Chemical Intermediates/Springer Netherlands | 2015 |
| 23 | BR Nagashree, HS Santosh Kumar, BR Gurumurthy, N Nataraja Karaba, MB Shivanna | PCR-based RAPD technique to determine induced salinity tolerance in vitro in Acacia auriculiformis | 1.39 | Plant Biosystems/Taylor & Francis | 2015 |
| 24 | Nagaraja Deeplanaik, Ramesh Chapeyil Kumaran, Krishna Venkatarangaiah, Hulikal Shivashankara Santosh | Expression of drought responsive genes in pigeonpea and in silico comparison with soybean cDNA library | 0.78 | Journal of Crop Science and Biotechnology/Springer Netherlands | 2014-01-09 |
| 25 | Tejaswini Subbannayya, Lavanya Balakrishnan, Granthali Sudarshan, Jayshree Advani, Santosh Kumar, Ri | An integrated map of corticotropin-releasing hormone signaling pathway | 3.82 | Journal of cell communication and signaling/Springer Netherlands | 2013 |
| 26 | Shrikanth Ulloora, Santhosh Kumar, Ramakrishna Shabaraya, Airody Vasudeva Adhikari | New dihydropyridine derivatives: anti-inflammatory, analgesic and docking studies | 1.277 | Medicinal Chemistry Research/Springer-Verlag | 2013 |
| 27 | BR Bharath, H Manjunatha, HS Santosh Kumar, K Bharath | Non Linear Flux Assessment Model for Endotoxin Neutralizing Pathways | 2.06 | J Computer Science and Systems Biology | 2013 |
| 28 | Sandeep Telkar, Hulikal Shivashankara Santosh Kumar, Riaz Mahmood | Synteny Approach of Drug Target Prediction among Unique Hypothetical Proteins of Streptococcus Gordonii Causing Infective Endocarditis | 1.235 | Science, Technology and Arts Research Journal/Wollega University | 2013 |
| 29 | Sandeep Telkar, Hulikal shivashankara Santosh Kumar, Nagaraja Deeplanaik, and Riaz Mahmood* | Strategic genome-scale prioritization of unique drug targets: A case study of Streptococcus gordonii | 0.6 | Bionformation/Biomedical informatics | 2013 |
| 30 | BG Harish, V Krishna, HS Santosh Kumar, BM Khadeer Ahamed, R Sharath, HM Kumara Swamy | Wound healing activity and docking of glycogen-synthase-kinase-3-β-protein with isolated triterpenoid lupeol in rats | 3.216 | Phytomedicine/Urban & Fischer | 2008 |
Books
| Sl No | Authors | Title | Publisher | Year |
|---|
Book Chapters
| Sl No | Authors | Title | Publisher | Year |
|---|---|---|---|---|
| 1 | Hulikal Shivashankara Santosh Kumar, Rachana Shankaraghatta Nagaraj and Gollapalli Pavan | FRONTIERS IN CURRENT ASPECTS OF ANTIMICROBIAL PEPTIDES FROM INSECTS AND THEIR THERAPEUTIC PERSPECTIVES | IIP Proceedings/Futuristic Trends in Biotechnology | 2022-11-08 |
| 2 | H. S. Santosh kumar , Vadlapudi Kumar | Biodiversity and Bionformatics | Pointer Publishers | 2013 |
Conferences
| Sl No | Authors | Title | Organizer | Year |
|---|---|---|---|---|
| 1 | Jayashree C. S. and Santosh Kumar H. S. | Comparative analysis of Rosetta stone events in pneumonia causing bacteria. | Somnogen Canada Inc. and All India Institute of Training and Education | 2023-05-13 |
| 2 | Deepthi S. Bharadwaj, H. S. Santosh Kumar | Gene expression analysis of LPS induced inflammation: Look who is talking | Presented at RSM-2022, School of Biotechnology and Bioinformatics, D Y Patil Deemed to be University | 2022-10-11 |
| 3 | Santosh Kumar H. S. Jayashree C. S. Chandrashekar C. R, Lavan S. Patil and Sriraksha Prakash | INVESTIGATION OF ROSETTA STONE EVENTS AMONG FEW PNEUMONIA PATHOGEN PROTEOME IDENTIFIES IMPORTANT VIRULENT PROTEINS | IABMS | 2021-11-25 |
| 4 | Pradeepa K, Prabhaker Walmik , Santosh Kumar H S , Vibha N and Anusha | Molecular docking analysis of novel indole derivatives against essential bacterial cell wall synthetic enzyme-Glmu | International Conference on Artificial Intelligence and Soft Computing (ICAISC-2021) | 2021-06-03 |
| 5 | H. S. Santosh kumar | Exploring Bioinformatics in cyberspace | AICTE – ATAL Sponsored FDP on “Bioinformatics for Engineers and Medicos” | 2020-09-28 |
| 6 | H. S. Santosh Kumar | Who is Unique in your PIN? | AICTE – ATAL Sponsored FDP on “Bioinformatics for Engineers and Medicos”, UBDT college of Engi | 2020-09-02 |
| 7 | Triveni N, Shyam kumar Vootla, Santosh kumar HS. | Antiviral Mechanisms in silkworm mediated through PI3k-AKT pathway | 59th Annual AMI Conference, University of Hyderabad, Hyderabad, Telangana | 2019-12-03 |
| 8 | Poornima R, Jayashree HN, Santosh Kumar HS | Rosetta stone Events as Tools for Searching New Drug Targets | 16th IAAM Annual Meet , JSS -Academy of Higher Education and Research - Oral Presentation | 2019-11-29 |
| 9 | Pooja N and Santosh Kumar HS | Cox2 inhibitors: Evaluating the Screening Bedrock | 39th IABMS summit and International conference on “Current concepts on the role of Indian medicine | 2019-11-17 |
| 10 | Praveen Kumar, Rajeshwar Achur, Santosh Kumar HS | In silico and invitro evaluation of quinoline-based pharmacological agents for inhibiting cancer cells growth | 39th IABMS summit and International conference on “Current concepts on the role of Indian medicine | 2019-11-17 |
| 11 | Naveen Kumar, Ravi Kumar S, Ajith Bhat, Santosh Kumar HS | Molecular Docking of Gyrase Inhibitors: Weighing earlier screening bedrock | International Conference on Affordable Strategies for Health and Environment ASHE-2019, Department o | 2019-05-05 |
| 12 | H. S. Santosh Kumar | Systems Biology – A primer for Biologists | Unravelling the Intricacies of Bioinformatics and Systems Biology for Sustainable Development, Depar | 2019-04-01 |
| 13 | Sunil Kumar V, Santosh Kumar HS, Niranjan P | Molecular Cloning and in silico characterization of Antimicrobial peptides from Trichogramma chilonis | National Conference on Synthetic and Biological peptides, Department of Chemistry, Bangalore Univers | 2019-03-14 |
| 14 | Sunil V, Ondara Zablon Kerima, Santosh Kumar HS, Niranjan P | Transcriptomic identification, molecular cloning and In silico characterization of esterases from T. Chilonis Ishii Targets | Emerging trends and Challenges in Life Sciences , Department of Biochemistry, Davanagere University | 2019-02-01 |
| 15 | Praveen Kumar, Santosh Kumar HS, Rajeshwar N Achur | Benzofuran and Quinoline analogues as potential anticancer agents | National Conference on Reaching the Unreached Through Science and Technology, Mangalore University a | 2017-09-09 |
| 16 | H. S. Santosh Kumar | Role, Significance and Applications of Bioinformatics in Biotechnology | Institution of Engineering students, NMAMIT chapter, | 2015-04-05 |
| 17 | H. S. Santosh Kumar | “Systems Biology: New “HOLISM” for understanding biology” | 33rd Annual Meeting of the Society of Reproductive Biology and Comparative Endocrinology, Department | 2015-02-02 |
| 18 | H. S. Santosh Kumar | Systems Biology: New Holism in analysis of Complex Biological Data | XII conference of Society of Cytology and Geneticists and Symposium on Challenges for Biologists in | 2014-12-23 |
| 19 | H. S. Santosh Kumar, Sharath Pattar and V. Kumar | “Interactome Analysis of Human WD40 Repertoire: Who is Important in Your Family?!” | 83 rd Annual Meeting of SBC (I) – 2014 , organized by KIIT University, Bhubaneshwar, ODISHA. | 2014-12-12 |
| 20 | H. S. Santosh Kumar | “Systems Biology-concepts and prospects for entomologists” | National agriGrid workshop at National Bureau of Agriculturally Important Insects, Bengaluru | 2013-11-30 |
| 21 | H. S. Santosh Kumar | Systems Biology: Concepts and prospects for entomologists | ICAR sponsored Workshop on Bioinformatics: In vitro to In-silico approaches in Entomology, NBAII, Be | 2013-04-24 |
| 22 | H. S. Santosh Kumar | “Bioinformatics – Developments, trends and future prospects” | National Workshop on Bioinformatics | 2012-03-30 |
| 23 | Santosh Kumar H. S. Bharath B. R, Sujata Barangi and Manjunatha H | “Non-Linear Flux assessment for Endotoxin Neutralizing Pathways” | International conference on Molecular Medicine – MOLMED – 2012 organized by VIT, Vellore, Tamil | 2012-02-19 |
| 24 | H. S. Santosh Kumar | “Bioinformatics- future perspectives” | UGC sponsored National symposium, VV Sangha college Bellary | 2012-02-17 |
| 25 | H. S. Santosh kumar | Bioinformatics: development, trends and prospects | National Workshop on Application of Bioinformatics tools in Biological sciences, Department of Biote | 2012-01-09 |
| 26 | Santosh Kumar H.S, SharathKumar Pattar, Ashwini.H.K. | POWER GRAPH ANALYSIS OF INTERACTOME: CASE STUDY OF Mycobacterium tuberculosis DNA REPAIR MECHANISM FOR DRUG TARGET IDENTIFICATION | MFOB conference, SDM college, Ujire - Invited talk | 2011-04-20 |
| 27 | Nagaraj D, Santosh Kumar H. S. and V. Krishna | “In silico analysis and evaluation of drought responsive genes in pigeonpea by comparing with the cDNA libraries of soybean leaf” | World congress in Biotechnology by the international Omics Group, Hyderabad. | 2011-03-21 |
| 28 | Sandeep Telkar, H. S. Santosh Kumar, Riaz Mahmood | “Ankyrin Repeats: Does Consensus-Virulence relate each other?” | ‘Bio-IT’ - JAIVIK 2010, held at GM Institute of Technology, Davangere, Karnataka, India. | 2010-02-24 |
| 29 | Bharath BR, H. S. Santosh Kumar | “Comparative analysis of homologous proteins for specific drug design” | International conference on Current Trends in Drug Design at CDRI | 2010-01-24 |
| 30 | Gollapalli Pavan and H. S. Santosh kumar | “Dynamical properties and Conformational flexibility of Mycobacterium tuberculosis HSP 60.2: MD simulations and Normal analysis approach" | Eighth Asia-pacific Bioinformatics conference held at J.N. Tata Auditorium, Indian Institute of Scie | 2010-01-18 |
| 31 | Sandeep Telkar, Santosh kumar H. S, Riaz Mahmood | “Horizontal genetransfer: A case study of being natural tool for pathogenicity among genome completed streptococcus causing Infective Endocardites” | 8th Asia Pacific Bioinformatics Conference, | 2010-01-18 |
| 32 | Navya V, H. S. Santosh Kumar | “Study on the Effects of Mutations on ligand Receptor Interaction with special reference to CYP2D6 and Debrisoquine” | National Symposiun on Antimicrobial Resistance and Drug Discovery. Deprtment of Microbiology. Dr N.G | 2009-09-09 |
| 33 | Tejaswini Hiremath, Archana HV and H. S. Santosh Kumar | “Genome wide analysis of human WD repeat protein repertoire” | National symposium on Role of Biotechnology in development of Herbal Drug and Conservation of Biodiv | 2009-01-24 |
| 34 | Niketan Lancer D Souza, Bharath BR, H. S. Santosh Kumar, Harish B. G | “Molecular Docking studies of novel drug molecules for the treatment of Alzhemer’s Desease” | National symposium on Role of Biotechnology in development of Herbal Drug and Conservation of Biodiv | 2009-01-24 |
| 35 | Prakash geriyol, H. S. Santosh Kumar, V. Vasudev | Anti mutagenic potential of Digoxigenin | “Indo-Australian conference on Human Variation and Pharmacogenomics”, Organized by Manipal unive | 2007-03-17 |
Articles
| Sl.No | Authors | Title | Publisher | Year |
|---|
| Sl No | Title | Funding Agency | Co-Investigator | Amount | Status |
|---|---|---|---|---|---|
| 1 | Cheminformatics and Virtual Screening of Bridged Heterocycle compounds for Drug repurposing against COVID19 | VGST, Government of Karnataka | Prof. N. D. Satyanarayana | 3 | On Going |
| Sl No | Investigator Name | Title | Year |
|---|
| Sl No | Name | Title | Research Degree |
|---|---|---|---|
| 1 | Mrs. Jayashree C. S. | “Genome-wide Analysis of Protein domain landscape of few Pneumonia causing Bacteria” | Ph.D. |
| 2 | A. Vinay Kumar | Effect of Lead (Pb) exposure on methylation markers of one carbon metabolism (OCM) among Pb exposed workers | Ph.D. |
| 3 | Ms. Deepthi S | Gene expression study of few inflammatory models for the identification of condition specific expression pattern | Ph.D. |
| 4 | Mr. kondhalkar Shridhar Jagannath | A Comprehensive assessment of environmental pollution and its biological responses among population living near Vrishabhavathi river basin. | Ph.D. |
| Sl No | Name | Title of Thesis | Research Degree | Year | Address | EmailId |
|---|