Department of Biotechnology
Dr. Kumaraswamy H MM.Sc., Ph.D,
Area Of Research
Cell Signalling, Medicinal Plants, Anti-cancer Therapeutics
About the Faculty
Short note from the faculty
Awards
| Sl No | Award Name | Award For | Organization | Year |
|---|---|---|---|---|
| 1 | Young Investigator Award | Oral pesentation- Smoking induced DNA damage results in ATM dependent phosphorylation of Histone H2AX in pancreatic cancer | American Pancreatic Association,USA | 2014 |
| 2 | CV Raman Post Doctoral Award Tenable in USA | Post Doctoral Research | UGC, New Delhi | 2013 |
Journals Publications
| Sl No | Authors | Title | Impact Factor | Publisher | Year |
|---|---|---|---|---|---|
| 1 | H. Muktha, R. Sharath, Nagaraju Kottam, H.M. Kumaraswamy, S. Srinath. | Carbon dots- A study of its cytotoxicity activity against HepG2 and MCF-7 cell lines | 0 | Materials Today: Proceedings. | 2021-05-14 |
| 2 | P. Meghana, Jain R. Sandeep Kumar, Telkar Sandeep, N. Prashanth, H.M. Kumaraswamy. | Acetogenins as potential checkpoint-2 kinase inhibitors: an in silico analysis. | 0 | Journal of Proteins and Proteomics | 2019-10-15 |
| 3 | Supriya Srinivasan, Venkatakrishna Jala, Kumaraswamy Honnenahally, Jason Castellanos, Praveen Kumar | Urolithin A prevents pancreatic tumor growth and increases survival by inhibiting PI3K/PDK1 and STAT3 signaling | 9.1 | Cancer Research | 2018-11-10 |
| 4 | Arunodaya Hosahalli Sumithregowda, Krishna Venkatarangaiah, Kumaraswamy Honnenahally, Vinaykumar | Cytotoxicity and Oral Acute Toxicity Studies of Litsea glutinosa C. B (ROB) Stem Bark Ethanol Extract. | 0 | Pharmacognosy Journal | 2017-08-01 |
| 5 | Mahadevappa Paramesha, Chapeyil Kumaran Ramesh, Venkatarangaiah Krishna, H. Malleshappa Kumar Swa | Effect of dehydroabietylamine in angiogenesis and GSK3- inhibition during wound healing activity in rats. | 1.43 | Springer: Med Chem Res | 2014 |
| 6 | Khadeer B. M. Ahamed Harish Basavanthappa Gowdru, Sharath Rajashekarappa Kumar Swamy H. Mal | Molecular docking of glycogen synthase kinase3-b inhibitor oleanolic acid and its wound-healing activity in rats. | 1.43 | Springer: Med Chem Res | 2012 |
| 7 | Harish B. Gowdru, Shrath Rajashekarappa, Kumara Swamy H. Malleshappa, Katenahally R. Maruth | In vitro regeneration of Inflorescence and callus enhancement of Celastrus paniculatus Willd. | 1.4 | Global Science Books: MAPSB | 2011 |
| 8 | R. Sharath, B.G. Harish, V. Krishna, B.N. Sathyanarayana and H.M. Kumara Swamy. | Wound Healing and Protease Inhibition, Activity of Bacoside-A, Isolated from Bacopa monnieri Wettest. | 2.66 | Wiley Online Library:. Phytother Res. | 2010 |
| 9 | B.G. Harish., V. Krishna., H.S. Santhosh Kumar, B.M. Khdeer Ahamed, R. Sharath, H.M Kumaraswamy. | Wound healing activity and docking of GSK3-β with lupeol isolated from Celastrus paniculatus Willd. | 3.5 | Elsevier: Phytomedicine | 2008 |
| 10 | Prabhakara, M. C., Naik, H. S. Bhojya, Krishna, V. and Kumaraswamy, H. M. | Binding and Oxidative Cleavage Studies of DNA by Mixed Ligand Co(III) and Ni(II) Complexes of Quinolo [3,2-b]Benzodiazapine and 1,10-Phenanthroline | 0.76 | Taylor and Francis:Nucleosides, Nucleotides and Nucleic Acids | 2007 |
| 11 | B.M. Khadeer Ahamed, V. Krishna., Harish B.Gowdru., H. Raja Naika, H.M. Kumaraswamy, R. Sha | Isolation of bactericidal constituents from the stem bark extracts of Grewia tiliaefolia Vahl | 0.2 | Academic Journals Inc:Research Journal of Medicinal Plants | 2007 |
| 12 | Kumaraswamy H.M., Krishna,V., Shankarmurthy,K., Abdul Rahiman,B, Mankani, K.L., Mahadevan,K | Wound healing activity of embelin isolated from the ethanol extract of leaves of Embelia ribes Burm. | 3 | Elsevier: Journal of Ethnopharmocology | 2007 |
| 13 | Harish B. G, Krishna,V. Sharath R, H.M. Kumara swamy, Raja naika H., Mahadevan K. M. | Antibacterial activity of celapanin, a sesquiterpene isolated from the leaves of Celastrus paniculatus Willd. | 0.35 | Int. J. Bio Med. Pharma. Sci | 2007 |
| 14 | Rajnaika H, Krishna .V, Vardaraj. N and Kumaraswamy H.M | Microppropogation and Evaluation of Genetic variability among in Vitro regenerants of Nervalia zeylanica | 0 | GSB: Med. Aroma. Plant Sci. Biotech | 2007 |
Books
| Sl No | Authors | Title | Publisher | Year |
|---|
Book Chapters
| Sl No | Authors | Title | Publisher | Year |
|---|
Conferences
| Sl No | Authors | Title | Organizer | Year |
|---|---|---|---|---|
| 1 | Jason Castellanos, Supriya Srinivasan, Kumaraswamy Honnenahally, Chanjuan Shi, Michael N Vansaun, Da | Oncogenic mutant KRAS modulates CREB activation through MEK-ERK and AKT signaling in pancreatic canc | AACR:Cancer Research | 2016 |
| 2 | Kumaraswamy Honnenahally, Chanjuan Shi, Xi Chen, Jason Castellanos, Nipun Merchant, Timothy Blackwel | γH2AX: A molecular marker of DNA damage response in smoking-induced pancreatic ductal adenocarc | AACR; Cancer Res | 2015 |
| 3 | 4.Jason Castellanos, Kumaraswamy Honnenahally, Chanjuan Shi, Nipun Merchant, Nagaraj Nagathihalli | GM-CSF induces CREB signaling pathways and modulates tobacco carcinogen-induced pancreatic tumorigenesis. | AACR: Cancer Research | 2015 |
| 4 | N. Nagathihalli, K. Honnenahally, H. Tanjore , F. Revetta , X. Chen ,J. Castellanos , C. Shi , N. Me | Smoking-Induced DNA Damage Results in ATM-Dependent Phosphorylation of Histone H2AX in Pancreatic Ca | wolterskluwer: Pancreas | 2014 |
Articles
| Sl.No | Authors | Title | Publisher | Year |
|---|---|---|---|---|
| 1 | Meghana P, Sandeep Kumar Jain R, Prashanth N & Kumaraswamy H M. | Phytochemical profiling and screening of protective effects of Artabotrys odoratissimus on H2O2 induced oxidative stress in HEK-293 cells and erythrocytes. | Botany Letters | 2020-07-22 |
| 2 | K.Lingaraju, R.B.Basavaraj, K.Jayanna, S.Bhavana, S.Devaraja, H.M.Kumaraswamy, G.Nagaraju, H.Nagabhu | Biocompatible fabrication of TiO2 nanoparticles: antimicrobial, anticoagulant, antiplatelet, direct hemolytic and cytotoxic properties. | Inorganic Chemistry Communications | 2020-02-06 |
| Sl No | Title | Funding Agency | Co-Investigator | Amount | Status |
|---|---|---|---|---|---|
| 1 | Acetogenins Modulate ATM Signalling in Nicotine induced Chemoresistance in Pancreatic Cancer. | DST | Nil | 2370000 | COMPLETED |
| 2 | Embelin Can Modulate Ataxia-Telangiectasia Mutated (ATM) Signalling In Nicotine Induced Chemoresistant Pancreatic Cancer | DST-SERB | Nil | 5210554 | COMPLETED |
| 3 | Evaluation of Antiarthritic Property of the Bioactive Constituents of Embelia ribes Burm. | UGC | Prof. V . Krishna | 914300 | COMPLETED |
| 4 | Design and development of tumor targeted Embelin loaded nanoparticles. | VGST-SMYSR | Nil | 500000 | COMPLETED |
| Sl No | Investigator Name | Title | Year |
|---|
| Sl No | Name | Title | Research Degree |
|---|---|---|---|
| 1 | Sandeep Kumar Jain R | Evaluation of Bioactive Principles from Garcinia talbotii Raizada. for their Therapeutic Potential | Ph.D. |
| 2 | Meghana P | Investigation and Screening of Bioactive ConstituentsFrom Artabotyrs odoratissimus R.Br. | Ph.D. |
| 3 | Prashanth N | Investigation of Therapeutic effect of Evodiamine on nicotine induced DDR in pancreatic cancer | Ph.D. |
| 4 | Samartha J R | Phytochemical profiling and Investigation of therapeutic value of wild vegetables Indigenous to Agumbe Rain Forests | Ph.D. |
| Sl No | Name | Title of Thesis | Research Degree | Year | Address | EmailId |
|---|